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Early osteopathic medical research took place in the colleges of osteopathic medicine and centered on investigations attempting to record purely osteopathic observations using measuring instruments that were available at the time. The A.T. Still Infirmary at the American School of Osteopathy (ASO) in Kirksville, MO, acquired an X-ray machine in 1898. William Smith, D.O., used the device to create angiograms of cadavers, using a medium of mercury in a base of tallow and beeswax and X-ray exposures as long as 70 minutes.
Between 1898 and 1899, J. Martin Littlejohn, D.O., reported on the impact of spinal manipulation, also at the ASO. On the West coast, Dain Tasker, D.O., reported on the effect of stimulation of the vagus nerve on the heart in 1901 in The Osteopath, the journal of the Pacific College of Osteopathy in Los Angeles.
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Another notable
early researcher was Louisa Burns, D.O. Dr. Burns was originally supported by the Pacific
College of Osteopathy to research physiology of the nervous system. Dr. Burns continued
her efforts, eventually emerging as the first full-time osteopathic medical researcher.
